The successful candidate will work as part of the scientific team to support the research and development of Carbometrics technology. We are looking for someone to join the team who has some experience of working in a synthetic chemistry/biology laboratory. To thrive in this role, the successful candidate will have specific, hands-on, experience in the field of bioconjugations, be able to work independently and be adaptable to new ideas and change, resourceful and self-motivated. The role is based within our innovative team in Bristol’s only dedicated scientific incubator: Science Creates (St Phillips Incubator) (see: www. sciencecreates.co.uk for more details). Carbometrics is a young, growing company and will offer the successful candidate an interesting and enjoyable work environment with a highly motivated team of scientists plus an opportunity to grow and develop scientific skills and experience.

 

Qualifications

Essential:

  • BSc in an appropriate field (Biochemistry/Biology/Chemistry/Biomedical Engineering)

Desirable:

  • Further qualifications in and appropriate field (MSc or PhD).

Skills & Experience

Essential:

  • Significant experience of working in a practical laboratory in academia and/or industry
  • Expertise and demonstrable experience in the field of bioconjugation (for example labelling of proteins, oligonucleotides, antibody-drug conjugates or other macromolecules)
  • Ability to work independently with good problem-solving skills
  • Excellent numeracy, literacy, and computer skills
  • Proficiency in key MS Office programs (Excel, Word)

Desirable:

  • Specific industry experience in a relevant context (i.e. in vitro diagnostics and/or medical devices)
  • Practical research experience (preferably of chemical biology and/or organic synthesis) in an industrial or academic laboratory
  • Ability to execute an experimental work plan; drawing on input/advice and feedback from the team leader and wider team
  • Experience with routine purification and analysis methods (including biomolecules)
  • Familiarity with supramolecular host-guest systems or substrate binding proteins: understanding of interactions between molecules or proteins, extraction and calculation of binding constants from data and how external factors (e.g. temperature, solvent medium) can affect a binding system
  • Experience of biologics assay development, optimisation and qualification
  • Experience for analytical chemistry, synthetic chemistry, fluorescence detection and biophysical techniques

Roles and Responsibilities

Core:

  • General shared facility housekeeping duties as part of the wider scientific team
  • Carry out bioconjugation R&D and analysis under the guidance of the CSO/Head of Research

Additional:

  • Maintain an excellent safety culture by timely reporting of all safety incidents and learning events
  • Execute an experimental work plan, drawing on input from the rest of the team
  • Document and timely reporting of all experimental work
  • Assist the team to ensure procedures are developed and kept up to date
  • Build strong, positive working relationships with team members
  • Actively contribute to continuous improvement by developing ideas to improve personnel safety, environmental aspects and process improvement.

Eligibility and Expectations

  • In order to qualify for this position, the candidate will need to be authorised to live and work in the UK
  • The candidate must have respect for others and a commitment and enthusiasm for high standards and continuous improvement
  • At Carbometrics we value diversity. We are an equal opportunities employer and welcome employees who meet the requirements of the job regardless of gender, ethnic origin, disability, age, religion or sexual orientation

Important information regarding your application:

Please note, we will not be confirming receipt of applications. Please include in your application confirmation of your consent for Carbometrics to hold your information and personal details for recruitment purposes. Applications without consent will be discarded.

With regards to an application, the procedure outlined will be followed:

  • Carbometrics will keep records of your application strictly for recruitment purposes
  • Any recruitment documentation will be kept for 12 months following the job position being filled
  • The successful candidates’ recruitment documentation will be kept in accordance with Carbometrics’ Internal Personal Data Policy

If you wish for your information to be removed from our records before that date, please contact our Head of Operations, Mrs Yvonne Olver via yolver@carbometrics.com stating “Personal information removal request” in the title of your email, or by writing to us at Carbometrics Ltd, Science Creates, St Philips Central, Albert Road, Bristol, BS2 0XJ.

 

To apply for this role in the first instance please forward your CV with a cover letter to: info@carbometrics.com stating “Senior Scientist Paternity Cover” in the title.

Expected Start Date: March 2023

Salary £32,000-£37,000 – dependent on experience

 

The deadline for this application is:

5.00pm Friday 24th February 2023